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OSU Develops New System For Freezing Human Tissue

Lots of human tissue is frozen, from blood to embryos.

But the size and complexity is constrained by ice crystals that form when frozen. Crystals can damage and even destroy a cell.

Researchers use what’s called a cryoprotectant, like the stuff you put in a car to stop the radiator water from freezing to reduce that damage. But cryoprotectants are toxic.

Now, Adam Higgins with Oregon State University says they’ve developed a new way of using cryoprotectants, “The way to reduce toxicity is to intentionally cause the cells to swell, but not swell too much," he said.

"And that swollen cell can take up more cryoprotectant at a lower concentration than an unswollen cell can.”

Higgins has been able to reduce damage in two dimensional tissue, lying on a petri dish. But now he has to show the process can work on larger, three dimensional tissue samples.

The findings were announced in the Public Library of Science.

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Cleaning Up Toxic Contaminants In The Willamette River

The National Remedy Review Board is meeting in Portland this week to consider the Environmental Protection Agency's (EPA) current strategy to clean up the Portland Harbor Superfund site.

The 11-mile stretch of the Willamette River was designated a Superfund site in 2000, and the EPA is charged with coming up with a strategy for cleaning it up.  Other nonprofits, community groups, tribes, municipalities and industry groups have already submitted their comments to the review board.

Human and ecological health is at risk from the chemicals that made their way into the river as a byproduct of industry and other human activity.

Barbara Smith, the spokeswoman for the Lower Willamette Group, which is made up of some of the potentially responsible parties — including companies like Northwest Natural and municipalities like the City of Portland. Smith told Think Out Loud that reducing the risks from the pollutants is the main goal of the Superfund cleanup. But she says each cleanup requires a mix of approaches:

"It isn't a one size fits all. And when you have a dynamic river system and an active harbor, like here in Portland, you really have to take into consideration the physical characteristics of the river. And a lot of the research that we've done has gone into determining  what works best where."

Some places, like the McCormick and Baxter site — the first in the harbor to get the Superfund designation — have been cleaned up already.

But much of the other cleanup will not move forward until the EPA comes out with final plan, expected next spring. Contaminants include heavy metals, PCBs, DDT, polycyclic aromatic hydrocarbons (PAH) from fossil fuels, and phthalates, which can interfere with human hormones. 

The broadly stated options for river cleanup, include: sediment removal (the most expensive option); capping the soil and sediment; and what's called "natural recovery," essentially leaving the river alone, with little to no intervention. 

Travis Williams, executive director of Willamette Riverkeeper, says what strikes him is how long we've known that toxics are a problem. He points out that Rachel Carson's "Silent Spring" — a seminal work documenting the health impacts from toxics in the environment — was published in 1962.

"And here we are, 50 some years later and we're still talking about leaving pollutants in the river, as if the natural river sediments of the Willamette can take care of [them] more than active remediation."

Cami Grandinette oversees Superfund cleanups for the EPA's region 10, which includes the Portland Harbor. She says that leaving contamination in a dynamic river system is not ideal, but cost is a factor for the agency.Grandinetti says the question is how to balance costs with human and environmental health.

"The goal of the Superfund program is a bit beyond reducing risks. There are clear criteria we have to achieve to actually protect human health and the environment. And so there, our goals are based on targets that reduce it to a certain level that we deem to be acceptable."

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'Oregon Healthiest State' Attracts 70 Partners In First Year

Health depends on a lot more than just the local health care system.

The economic stability of families; their education levels; physical fitness; even their eating habits play an important role.

To improve all those issues at once, the 'Oregon Healthiest State' was started last year.

It aims to get all kinds of organizations to work together, from businesses to government agencies and charities.

Oregon Health & Science University president Joe Robertson said signing up 70 partner organizations is a start, “I think all social movements take time and they’re slow to gain momentum," he said. 

"But if you can gain enough momentum, they tend to carry themselves," said Robertson. Oregon’s well-being score has dropped since 2008 when it ranked 19th in the nation. It now ranks 27th.

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Study Ranks Oregon Last For Mental Health Care

Michael Clapp/OPB

A study looking at mental health care among states has ranked Oregon dead last.

The president of Mental Health America, Paul Gionfriddo, said researchers considered 13 elements for the ranking: from the number of residents with mental illness to access to care.

“Oregon does generally poorly on the prevalence of mental illness ranking," he said. "In other words, there are more children and adults with mental illnesses; with dependence on alcohol or drugs; with serious thoughts of suicide.”

The study also looked at factors like how many people have access to insurance, whether that insurance is adequate, and how high are the barriers to accessing mental health care. 

Minnesota was ranked at the top of the list for its mental health care, while Idaho and Washington also ranked near the bottom — coming in at 45th and 47th, respectively. 

When looking only at access to care, Oregon did better in the study, ranking 21st. 

Despite the low ranking, Chis Bouneff with the Oregon chapter of the National Alliance on Mental Illness defended mental health care in the state, saying the data used were from 2013.

“It's very old data," he said.

"Oftentimes the difference between 2015 and 2013, those two years, may not be a big deal. But because you had a seminal event under the Affordable Care Act, in that we expanded Medicaid, it’s hard to look at this data right now and use it to really inform future policies,” Bouneff said.

Both Bouneff and Gionfriddo say they expect Oregon to do better when new data are included next year.

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Portland Has Lowest Preterm Birth Rate In Nation

Portland has the lowest rate of preterm births of any city in the nation — according to a new study by The March of Dimes.

After decades of increases, the rate of premature birth in the U.S. is now declining. But not fast enough, according to the charity March of Dimes.  So it graded 100 cities on their rates.

At 7.2 percent, Portland's rate was much lower than anywhere else. Nationally, about 9.6 percent of births are preterm.

Aaron Caughey, the chair of the department of obstetrics at OHSU, said: "One of the reasons why we can do things here in Oregon that might be harder in other states, is there’s a willingness to work together with disregard of our own personal agenda, our own personal egos, to the best outcomes for the women that we care for.”

Babies born before 37 weeks can suffer from short-term breathing and heart problems, as well as long-term complications like cerebral palsy and poor vision.

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Providence And PeaceHealth Announce Joint Wellness Center In Vancouver

A couple of days after two of Oregon’s largest health care organizations announced a merger, two competitors say they’re also going to collaborate.

PeaceHealth and Providence have signed a letter of intent to develop a new health and wellness center in Vancouver, Washington.

They companies said it’s the first of multiple initiatives.

Dave Underriner, CEO of Providence in Oregon, said his organization and health care services around the nation are reacting to the Affordable Care Act.

“I think you’re going to see all sorts of partnerships and affiliations and collaborations, different ways for organizations to come together to work in concern, in terms of serving communities,” he said.Underriner said the PeaceHealth Providence collaborative will likely result in more jobs — both from building the new center and staffing it.

The recently announced merger between Legacy and PacificSource is also expected to create jobs.

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Oregon To Restructure Health Insurance For State Employees

The state has voted to restructure health care premiums for its employees, to avoid paying the federal government’s new "Cadillac Tax."

The Cadillac Tax goes into effect in a few years. It will take money from people who have high-end health insurance plans to help pay for all the additional people who now have insurance under the Affordable Care Act.

The state’s existing individual employees plans would trigger the tax, costing the state more than $300 million.

Kathy Loretz of Oregon’s Public Employee Benefit Board, or PEBB, says the state is re-balancing premiums so they won’t trigger the tax.

“What is going to happen is that employee premiums are going to go down a little bit, and the employee and family group will go up," she said.

"So total premiums will end up being the same from PEBB's point of view. However, how it is distributed is different.”

Union members on the PEBB board voted for the change, meaning there shouldn't be much opposition to the change.

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