Image Oregon Health & Science University and SEIU Local 503 held a vaccine clinic at the Oregon Convention Center./Josh Andersen/OHSU Is Your Covid Vaccine Venue Prepared to Handle Rare, Life-Threatening Reactions? Of the more than 6 million people in the U.S. who have received a COVID-19 vaccine shot, about 30 have suffered a severe allergic reaction -- about five times the rate for flu shots. Jan 11, 2021 Subscribe to CDC. health care